top of page
Science Farm Ltd.

Pipelines
Systemic sclerosis
Systemic sclerosis is an intractable disease characterized by collagen deposition and fibrosis of skin and organs. Supportive treatment to relieve symptom is a sole remedy.
We found a compound HPH-15 that suppresses the collagen production in fibroblast. HPH-15 ameliorated the skin thickness of systemic sclerosis model mice.
HPH-15 is currently at pre-clinical study. We are collaborating with dermatology department of Kumamoto University Hospital.





Eradication of AIDS
Owing to the recent anti-HIV drugs symptoms of AIDS became amenable to control. However, since HIV latently survives in the patient's body, the disease recurs by interruption of drugs.
We developed a novel drug that encloses the HIV inside the host cells and kills HIV together with the host cells. This would lead to the eradication of AIDS.
Neuroprotectants
Cerebral infarction is a blockade of brain arteries resulting in ischemia and cerebral cell death. This process is suppressed by neuroprotectants.
We developed a new compound CNN that scavenges toxic substance HNE produced by cerebral ischemia. CNN showed effect in Mongolian Gerbil ischemia model, as demonstrated by a collaboration with department of neurosurgery, Kurume University.
Phytic acid prodrug
Phytic acid shows a range of biological activities, i.e., anti-cancer, anti-diabetic, immuno-potentiating, kidney stone-protecting, cholesterol-lowering, and coronay artery disease-preventing effects. However, due to low cell permeability, there has been limitation in cellular study for drug development.
We developed a cell-permeable prodrug that release the parent phytic acid in cells, promising for life science study as well as drug development.

bottom of page