Neuroprotectants

 Cerebral infarction is a blockade of brain arteries resulting in ischemia and cerebral cell death. This process is suppressed by neuroprotectants.

 Edaravone, the sole approved neuroprotectant, quenches free radical generated by cerebral ischemia. We developed CNN that quenches HNE, the toxic end product of ischemia.

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 CNN showed effect in Mongolian Gerbil ischemia model, as demonstrated by a collaboration with Professor Motohiro Morioka, department of neurosurgery, Kurume University.

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